Vaccines: making responsible decisions

Articles and reflections from the Academicians

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Vaccines: Making responsible decisions, Father Carlo Casalone SJ, La Civiltà Cattolica - Full text

(...) Regarding vaccines, there is a distorted perception of risk compared to the objective assessment of the danger, given the clearly favorable and well-documented benefits and risks. Certainly the fact that the people to be treated are healthy can affect matters, but this reason is not sufficient to explain the phenomenon of resistance, since interventions in which this relationship is much less favorable are much more socially accepted.

These notions were already clear to Cardinal Consalvi, as we have seen, but today are emphasized by other factors. On the one hand, greater importance is given to the patient in his or her relationship with the doctor, which is certainly legitimate but not always easy to calibrate. On the other hand, there is a generalized crisis of trust in human relationships, both personally and in structured and institutional forms. Pope Francis puts it very simply: “I do not know why someone says: ‘no, the vaccine is dangerous.’ If the doctors present it to you as something that can go well, that has no special dangers, why not take it?”. A simple argument, but full of wisdom. In fact, researchers note that the perception of risk is a predominantly unconscious cognitive process, affected not only by the probability of damage that you can suffer by exposing yourself to a danger, but also, and above all, by an emotional component, consisting of a set of feelings, such as fear, resentment and anger. While the probability of damage in the face of danger can be calculated objectively – and this is the task of experts, as the pope says – the emotional component depends on a multiplicity of variables.

Therefore, it is not enough to field logical arguments and scientific data on a biomedical and statistical level: it is necessary to involve the emotional and relational levels, in which behaviors are rooted. Moreover, a widespread climate of mutual trust is of great importance, which is the result of serious and honest attitudes in the habitual fabric of social coexistence. There is even a specific area of health communications that examines these multiple elements in their various dimensions. (...)


Statement from Pro-Life Catholic Scholars on the Moral Acceptability of Receiving COVID-19 Vaccines

March 5, 2021

Note: EPPC has organized the following statement from leading pro-life Catholic scholars, including EPPC President Ryan T. Anderson, EPPC board member and Princeton professor Robert P. George, and EPPC Fellow and Notre Dame professor O. Carter Snead, along with two professors at pontifical universities in Rome and other U.S.-based scholars, to explain why it is morally acceptable for pro-life citizens to receive any of the COVID-19 vaccines currently available.

The past year of suffering under the onslaught of COVID-19 has brought with it numerous ethical questions, and the advent of effective vaccines for COVID is no different. Foremost among the questions for those of us who are committed to defending the intrinsic equal dignity of all human beings from conception to natural death are these: in accepting any of the vaccines on offer, is one in any way endorsing or contributing to the practice of abortion, or is one in any way showing disrespect for the remains of an unborn human being? As to the vaccines currently or soon available in the United States, we agree with Bishop Kevin Rhoades, Chairman of the USCCB Committee on Doctrine, that the answer is no. While there is a technical causal linkage between each of the current vaccines and prior abortions of human persons, we are all agreed, that connection does not mean that vaccine use contributes to the evil of abortion or shows disrespect for the remains of unborn human beings. Accordingly, Catholics, and indeed, all persons of good will who embrace a culture of life for the whole human family, born and unborn, can use these vaccines without fear of moral culpability.

Common to the four major vaccines, produced by Moderna, Pfizer, Johnson & Johnson, and AstraZeneca is some use of “immortalized” human cell lines. Ordinarily, cells taken from a body have a limited life span, undergoing only a fixed number of cell divisions before they arrest and die. For ongoing research, scientists prefer to use a “cell line,” or a population of cells derived from a single source that has been modified (typically by some form of genetic mutation) to divide indefinitely in culture. Such “immortalized” cell lines allow scientists to conduct many experiments on cells that are both genetically identical and routinely available in the laboratory.

HEK293 is one such commonly used line.[1] The name “HEK” stands for “human embryonic kidney,” and “293” refers to the 293rd experiment conducted by the scientist who produced the cell line. The embryonic kidney cells were originally obtained from the remains of a deceased unborn child following what appears to be an elective abortion that took place in the Netherlands during the early 1970s. The exact circumstances of the abortion are not known, but the scientists producing the cell line were not directly involved and, crucially, the abortion was not performed for the sake of providing biological materials to researchers.

HEK293 cells are particularly susceptible to the introduction of foreign DNA, and they rapidly became a standard scientific workhorse, that is widely used by both basic scientists and by industry. Although there are currently many modified versions of HEK293s that optimize these cells for specific purposes, all of the HEK293 cells available around the world today were derived from the remains of a single unborn child that was aborted a half a century ago. Importantly, there is no ongoing use of aborted tissue to generate HEK293 cells, to modify these cells, or to maintain them in the laboratory. Thus, the use of HEK293 (and similar immortalized lines) does not create future incentives for more abortions.

How widely used are HEK293 cells? They are commonly used for testing processed foods produced by companies such as Kraft, Nestlé, Cadbury and others. Indeed, the great majority of processed/packaged food products available for sale in the United States are likely to contain ingredients produced or tested in HEK293 cells.

They are also used as an alternative to animal testing in the cosmetic and pharmaceutical industry. And their use in biomedical research is ubiquitous and has contributed to an enormous number of new medications and medical procedures developed over the last several decades. It thus seems fair to say that in addition to the use of HEK293 cells by the scientific community, nearly every person in the modern world has consumed food products, taken medications or used cosmetics/personal care products that were developed through the use of HEK293 cells in the food, biomedical and cosmetic industries.

The various vaccines have made different uses of the HEK293 cell line, with Johnson & Johnson and AstraZeneca using them for manufacture, Pfizer and Moderna for testing only. But these differences are irrelevant to the following questions:

  • Do any of the vaccines make more use than others of the mortal remains of unborn children from whom the cell lines were derived? The answer is no; as a matter of scientific fact, no fetal “body parts” are present in these immortal cell lines. The immortal cell lines are artifacts—biological products that have been modified and reproduced many times over, and they do not retain the natural function of the tissue from which they were derived. They are not “body parts” in any meaningful or morally relevant sense.
  • Does the production and use of any of the vaccines contribute to, cooperate with, or promote any abortion? Again, the answer is no, for the abortions from which cell lines such as HEK293 were derived happened decades ago, and no further fetal tissue is used or needed for the maintenance of these lines.

Common to all pro-life witness is recognition that the apparent elective abortion that led to the derivation of the HEK293 cell line was morally impermissible and involved the unjust taking of a human life. But to repeat, the HEK293 cell line currently used around the globe in scientific research and those like it do not contain the remains of any human being and so its use does not show disrespect for human remains, any more than the contemporary use of products, such as roads or train lines, that were constructed by unjustly enslaved human beings, or use of land unjustly taken, shows disrespect for those victims in the distant past.

As a descriptive matter, some pro-life advocates may prefer to use one vaccine rather than another in order to witness against the evil of abortion, or to signal special respect for the unborn babies whose lives were lost. Again, we agree with Bishop Rhoades that such a choice is a matter for their conscience. But we think it a mistake to say both that these vaccines are morally permissible to use and yet that some ought to be preferred to others. There appears to us to be no real distinction between the vaccines in terms of their connection to an abortion many decades ago, and thus the moral starting point is one of equivalence.

Moreover, there might be good reasons for some persons to prefer or to promote the vaccines, such as Johnson & Johnson, that use HEK293 (and PER.C6) for manufacture rather than testing, namely, that the J&J vaccine requires only one dose, does not require storage at extremely low temperature, and thus may be more useful in reaching remote or otherwise underserved populations. Those who have special reasons to take the J&J vaccine should not, we believe, be led to think that they are choosing something that in other ways is more morally tainted than the Pfizer or Moderna vaccines.

Persons with access to these vaccines have strong moral reasons to take them: in doing so, they build up the herd immunity that will provide the greatest possible protection for the most vulnerable among us, including the elderly, those with pre-existing conditions, some minority populations, and the many other seemingly random victims of severe COVID-19. To be perfectly clear, we are not saying that people are justified in using and promoting these vaccines because the great goods they provide offset the evil of appropriating a prior wicked action. Rather, we believe that there is no such impermissible cooperation or appropriation here. The attenuated and remote connection to abortions performed decades ago and the absence of any incentive for future abortions offer little if any moral reasons against accepting this welcome advance of science.


Ryan T. Anderson, Ph.D., President of the Ethics and Public Policy Center

Father Nicanor Pier Giorgio Austriaco, O.P., Ph.D., S.T.D., Professor of Biology and of Theology, Providence College

Maureen Condic, Ph.D., Associate Professor of Neurobiology, University of Utah

Father Kevin Flannery, S.J., Ph.D, Emeritus Professor of Philosophy, Pontifical Gregorian University

Robert P. George, J.D., D.Phil, D.C.L., D.Litt., McCormick Professor of Jurisprudence, Princeton University

O. Carter Snead, J.D., Professor of Law and Director of the de Nicola Center for Ethics and Culture, University of Notre Dame

Christopher Tollefsen, Ph.D., Distinguished Professor of Philosophy, University of South Carolina

Father Thomas Joseph White, O.P., D.Phil., Professor of Systematic Theology, Pontifical University of St. Thomas Aquinas – Angelicum

Affiliations provided for identification purposes only.

[1] We believe that the same analysis applies to the use of the immortalized cell line “PER.C6”, used in the Johnson & Johnson vaccine, derived thirty-one years ago using the remains of an unborn baby following an elective abortion obtained for reasons entirely disconnected to the creation of the line.









From National Catholic Reporter


All vaccines are morally acceptable, says member of Pontifical Academy for Life.

Any moral wrong is in the action of abortion, not in the vaccines themselves

Mar 5, 2021 by M. Therese Lysaught

(...) Catholics are not gnostics. We do not designate any aspect of God's good creation as "morally compromised" in and of itself. And, as we know from the Gospels, we cannot become "morally tainted" from any aspect of God's good creation (Matthew 15:11).

Again, I am sure the recent statements are no doubt motivated by sincere concerns about abortion. But they miss the mark. Current vaccines have no relationship with contemporary abortions. Thus, whether one receives or avoids a particular vaccine neither impedes nor advances the industry. Certainly, as every Vatican statement on this topic has made clear, the church remains committed to advocacy efforts aimed at "ensuring that every vaccine has no connection in its preparation to any material originating from an abortion." But putting human lives at grave risk of mortality or lifelong morbidity is not an ethical advocacy strategy. (...)